Khatarta Kansarka Mukhaadaraadka Maandooriyaha iyo Khatarta Khatarta Kansarka
Daawooyinka bacriminta ma keenaan kansar? Ka warran daaweynta IVF ? Waa run in daraasado yar oo u muuqda in ay u arkaan xiriirka u dhexeeya isticmaalka daroogada bacriminta iyo khatarta sii kordheysa ee kansarka naaska ama kansarka, gaar ahaan daroogada Clomid .
Dhammaan daawooyinka, oo ay ku jiraan daawooyinka bacriminta, waxay la yimaadaan halis.
Laakiin waa inaad ka walwashaa halista kansarka oo kordhay? Aan fiirino.
Maandooriyeyaasha Dumarka oo Kordhi kara ... ama Yaree Halista Kansarkaaga?
Sannadkii 2005, baaritaan ballaaran oo la soo bandhigay ayaa sheegay in isticmaalka isticmaalka Clomid uu kordhin karo halista kansarka uterininka .
Si kastaba ha noqotee, tan iyo wakhtigaasi, daraasado badan ayaa la sameeyay, badankoodna ma helin koror weyn oo khatarta kansarka ka dib isticmaalka Clomid.
Dhab ahaantii, mid ka mid ah daraasaddan ayaa muujisay, in dumarka lagu daweeyo daawooyinka bacriminta ay u muuqdaan inay muujinayaan halista hoos u dhaca qaadista kansarka ilmo-galeenka marka la barbar dhigo dumarka aan khatarta lahayn ee aan daweynin.
Daraasad kale ayaa laga helay halis yar oo ah inuu ku dhaco kansarka naasaha ka dib Clomid.
Waa maxay sababta isdhaafka?
Dhibaatada badan oo ka mid ah daraasaddan ayaa ah inayan tixgelin waxyaabah kale ee suurtogalka ah ee kansarka uterineinka.
Midaas, haddii qof dumar ahi marnaba uur yeelato, khatarta kansarku way korodhaa.
Sidoo kale, cayilku ma aha oo kaliya halista asaasiga ah ee dhalmo la'aanta , laakiin sidoo kale waa halis u ah kansarka.
Waxaa laga yaabaa inaysan aheyn daawooyinka bacriminta oo dhan.
Taa baddalkeeda, dhacdooyinka sii kordhaya waxaa loo aaneyn karaa sababaha ka dambeeya dhalmo la'aanta, ama tiro kasta oo ah arrimo kale oo aan lagu xisaabtamin daraasaddan.
Daraasado badan ayaa laga helay xiriir suurto gal ah oo ka dhexeeya sababaha keena dhalmo la'aanta iyo khatarta sii kordheysa ee kansarka.
Dhibaatada kale ee ka jirta daraasaddan ayaa ah xajmiga saamiga aad u yar.
Halis daroogada iyo Xakameynta Awood-darrida Kale ee kale
Calaamadaha ugu xoogan ee Clomid iyo daroogada kale ee xayawaanka ku kiciya ayaa kordhin waaya khatarta kansarka ugxan-la'aanta ah ay ka timaaddo Cochrane Review, oo la daabacay sanadka 2013.
Dib-u-eegista waxaa ku jiray daraasado laga soo bilaabo 1990 ilaa Febraayo 2013. Daraasadaha ayaa lagu soo ururiyey 182,972 haween ah.
Toddoba daraasadood ma helin caddayn ku saabsan kansarka ugxan-badan ee dumarka isticmaala daroogada bacriminta (oo ay ku jirto Clomid) marka la barbar dhigo khatarta ay u leeyihiin dumarka kale ee dhibaatooyinka bacriminta aan isticmaalin mukhaadaraadka bacriminta.
Sida laga soo xigtay dib u eegista, daraasadaha helay helitaanka khatarta kansarku ma ahan kuwo lagu kalsoon yahay sababtoo ah waxay ku fashilmeen in ay tixgeliyaan halista dhalmo la'aanta ama tirada saamiga aad ayay u yar tahay in la soo gabagabeeyo.
Xuduudaha Xanuunada Xoolaha iyo IVF?
Dib-u-eegista Cochrane waxay ka heshay khatar sare oo suurtagal ah inay ku dhacdo qanjidhada xuduudaha ee xuduudaha ee haweenka kuwaas oo maray daaweynta IVF.
Khatartaas ma aysan jirin wax keli ah ka dib Clomid ama Clomid oo leh daaweynta gonadotropins oo keliya.
Daaweynta qanjidhada xuduudaha ee xuduudaha ah ma aha mid aad u daran oo ku lug leh sida burooyinka caadiga ah ee ugxan-sidaha, iyo saadaasha dumarka leh xajmiga xuduudaha waa mid aad u wanaagsan.
Daraasad 2015-ka ah ayaa isku dayey in ay sii baaraan khatarta suurtagalka ah ee ku dhaca bararka xuduudaha ee xuduudaha iyo daaweynta bacriminta.
Waxa ay ogaadeen waxay ahayd in aysan jirin xiriir xooggan oo u dhaxeeya burooyinka xuduudaha ee xuduudaha iyo isticmaalka maandooriyaha.
Si kastaba ha noqotee, waxaa jiri kara xiriir suurto gal ah oo dhexda u dhexeeya burooyinka xiniinyaha ee xuduudaha iyo taageerada progesterone.
Cilmi-baadhayaashu waxay ogaadeen in halista uur-xuduudaha uur-jiifku ay ka sarreeyaan haweenka isticmaala progesterone marka loo eego kuwa aan weligood qaban, iyo in ka badan haweenka ku jiray afar ama kabadan lakabyo dheeri ah oo progesterone ah.
Taasi waxay tiri, tirada haweenka daraasaddan la leh burooyinka xadka waa yaraa.
Daraasado la socoshada kooxo waaweyn oo dumar ah ayaa loo baahan yahay.
Khatarta Kansarka Dhaawaca Cudurka ah?
Daawooyinka bacriminta miyuu kordhin karaa halista kansarka endometrial?
Dib-u-eegista Cochrane ee 19 daraasadood ayaa ku soo gabagabeysay sababtoo ah naqshadaynta daraasadda saboolka ah, suurtagal ma aha in la yiraahdo wax kasta oo hubaal ah in khatarta ugu dambeysa ee kansarku ay korodho ka dib marka la qaado daawooyinka bacriminta.
Waxaa loo maleynayaa inay tahay halis sare oo suurtogal ah ee dumarka oo qaatay qiyaaso badan oo Clomid ah (ka weyn 2,000 mg-celceliska qiyaasta bilowga ah waa 50 mg oo kaliya) waxana ay Clomid qaadatay toddoba ama kabadan.
Hase yeeshee, cilmi baarista hadda ma aysan awoodin in ay kala soocaan haddii khatarta korodhka ahi ay sababtay Clomid ama sababaha bacriminta ee hooseeya. Tusaale ahaan, PCOS waxaa loo yaqaanaa inay kordhiso halista ah in la horumariyo kansarka sanbabada.
Khatarta Cudurka Waqtiga-dheer ee Kansarka Naaska Ka dib IVF
Daaweynta daweynta ee IVF ma kordhin kartaa halista kansarka naasaha? Cilmi-baarista hadda waxay leedahay maaha.
Daraasadda ugu weyn ee taariikhda la sameeyay waxaa ka mid ahaa 25,108 haween ah, oo celcelis ahaan la socotay 21 sano ka dib daaweyn. Kuwani waxay ahaayeen haween ka tirsan Netherlands, kuwaas oo heley daaweynta IVF intii u dhaxaysay 1980 iyo 1995.
Ma jirin wax halis ah oo ku kordhay kansarka naasaha ee dumarka qaatay IVF marka la barbar dhigo kuwa qaata daaweynta bacriminta kale (laakiin maaha IVF.)
Waxa xiiso leh, cilmi-baarayaashu waxay ogaadeen in halista kansarka naasku ay yar tahay haweenka lahaa 7 ama wax ka badan wareegyada IVF marka loo barbar dhigo dumarka lahaa 1 ama 2 wareegyo. Ma cadda sababta ay tani tahay.
IVF iyo Cancer Ovarian
Munaasabadan oo lagu soo bandhigay cilmi-baaris ku saabsan HIV / AIDS-ka oo la yiraahdo Dr. Alastair Sutcliffe, oo ka tirsan Machadka Caafimaadka Ilmaha ee University College London, ayaa soo bandhigay daraasad eegaysa khatarta kansarka ee haweenka soo maray daaweynta IVF .
Daraasaddan waxaa ka mid ahaa in ka badan 250,000 oo haween ah oo Ingiriis ah iyo wareegyo daaweyneed intii u dhexaysay 1991 iyo 2010.
Warka wacan wuxuu ahaa in aysan helin halis dheeraad ah ee kansarka naaska ama kansarka ku dhaca bukaanada hore IVF.
Warka xun ayaa ah in la helo halis dheeraad ah ee kansarka ugxansidaha.
In kastoo dumarka aan waligood ku soo marin IVF waxay 11 jeer ku qaadatay 10,000 oo ah inay ku dhacdo kansarka ugxansidaha, bukaanka IVF waxay lahaayeen 15 10,000 oo dhicis ah.
Khatartu waa yar tahay laakiin waa muhiim in la aqoonsado.
Sida daraasadaha kor ku xusan, ra'yiga ayaa ah in khatarta kordhaysa aysan sababin daaweynta IVF lafteeda balse xaqiiqda ah in haweenku u baahan yihiin daaweyn.
Infertility iyo baahida loo qabo IVF ayaa loo maleynayaa inay halis tahay. Ma aha daawooyinka bacriminta loo isticmaalo inta lagu jiro daweynta.
Iyadoo taas la sheegay, daraasaddan ayaa sidoo kale lagu ogaaday in halista kansarku ay sare u kacday saddexdii sano ee ugu horreysay ka dib markii daweyntu socotay .
Sidaas awgeed, maaha suurtagal in la gooyo, in dawooyinka bacriminta ay kaalin ku yeesheen halista kansarka. Kormeerka dhow ee sannadaha ka dambeeya daaweynta IVF ayaa noqon karta mid caqli badan.
Lama kordhiyo Khatarta Kansarka
Falanqaynta maadada waa baadhitaan cilmi-baaris ah oo ururiya macluumaadka daraasado dhawr ah isla markaana qiimaynaya iyaga. Jaamacadda Ottawa waxay sameysay falanqeyn miisaan si loo eego in isticmaalka daroogada bacriminta ay kordhisay khatarta kansarka marka la barbar dhigo dumarka aan khatarta lahayn ee aan la daweyn.
Falanqaynta waxaa ku jiray xogta ay soo uruurisay toban cilmibaaris oo cilmi baaris ah, iyada oo macluumaadka ku saabsan haweenka qaadashada daawooyinka bacriminta sida Clomid, gonadotropins , goryadotropin bini'aadamka ah (HCG) , iyo gonadotropin-sii- doo-goyska hormoonka ah (GnRH).
Cilmi baarayaashu waxay ogaadeen in marka la barbardhigo dumarka aan khatarta lahayn ee lagu daaweeyo daawooyinka bacriminta, ee ka dhanka ah dumarka aan khatarta lahayn ee aan la daweyn, kuwa lagu daaweeyo daawooyinka bacriminta maaha halis dheeraad ah oo lagu kobcin lahaa kansarka ilmo-galeenka.
Inta badan si xiiso leh, waxay ogaadeen in haweenka la daaweeyay ay u muuqdaan inay hoos u dhaceen kansarka ugxan-sidaha marka la barbar dhigo dumarka aan khatarta lahayn ee aan la daweyn.
Daraasad kale oo ay samaysay ururka cilmibaadhista kansarka ayaa cilmi baaris ku samaysay 54.362 oo dumar ah oo aan dhalays lahayn. (Daraasadda wada hadalka waa marka ay eegaan kooxo dad ah oo leh xaalado isku mid ah, caadiyan mudo dheer.)
Daraasaddan, cilmi baarayaashu ma helin halis dheeraad ah ee halista kansarka naasaha ka dib isticmaalka daroogada bacriminta, gaar ahaan gonadotrophins , Clomid , hCG , ama GnRH .
Daraasado kale ayaa helay natiijooyin isku mid ah.
Erey Aan ka soo Baxay
Wadaxaajoodka ayaa ah in daawooyinka bacriminta aysan kordhinin halista aad ugu jirto inaad qaaddo kansarka naasaha ama kansarka. Sidoo kale, daraasadaha qaarkood waxay eegeen isticmaalka mukhadaraadka bacriminta iyo noocyada kale ee kansarrada (tusaale ahaan kansarrada iyo kansarka maqaarka, tusaale ahaan), waxayna sidoo kale ka heleen wax halis ah oo halis ah.
Si kastaba ha noqotee, maxaa yeelay bacriminta laf ahaanteeda ayaa ah arrin halis ah oo ku saabsan kansarka, la socosho kadib marka la ogaado cudurka.
Haweenka qaba ilmo-galeenka hoose-dhexe, kuwaas oo aan weligood uur qaadin oo dhalin, iyo sidoo kale haweenka laga helo endometriosis , ayaa laga yaabaa inay gaar ahaan halis dheeraad ah u yeeshaan kansarka.
PCOS , oo sabab u ah dhalmo la'aanta, ayaa sidoo kale loo yaqaanaa inay la timaado khatarta sii kordheysa ee lagu horumarinayo kansarka sanbabada. Waxaa macquul ah in qiyaaso badan oo Clomid ah, ama daaweyn ay ka sii dari karto todobo wareeg oo kabadan, waxay kordhin kartaa halista kansarka endometrial. Hase yeeshee caddaynta hadda jirta ma kala saari karto haddii khatarta korodhku ay ka imanayso Clomid ama infertility lafteeda.
Sidoo kale, waa muhiim inaad maskaxda ku hayso in farsamada daaweynta bacriminta ay isbedeleyso. Daawooyinka hooseeya ee daawooyinka hadda ayaa loo isticmaalaa marka loo eego maalmaha hore ee daaweynta , iyo in badan oo ka mid ah daraasadaha ku saabsan kansarka iyo daaweynta bacriminta waxaa ka mid ah haweenka la daweeyey 1980-yari, si ka daran sidii ay maanta noqon lahaayeen.
Daraasadaha ku saabsan kansarka iyo daaweynta bacriminta waxay kaloo u baahan yihiin dabagal dheer. Waxay noqon kartaa tobaneeyo sano ka hor inta aan run ahaantii sheegi karno saameynta saameynta bacriminta da'diisu tahay 35 jir waxay yeelan doontaa haweeney 65 jir ama 70 jir ah. Inkastoo ay tahay in cilmi baaris dheeraad ah la sameeyo, hadda, daawooyinka bacriminta ayaa (inta badan) ka soo baxaya jiirarka.
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